Abstract Gliomas are the most common central nervous tumors in children and adolescents.However, spinal cord low-grade gliomas (sLGGs) are rare, with scarce information on tumor genomics and epigenomics.To define the molecular landscape of sLGGs, CHILD we integrated clinical data, histology, and multi-level genetic and epigenetic analyses on a cons

Abstract Background Kinome profiling aims at the parallel analysis of kinase activities in a cell.Novel developed arrays containing consensus substrates for kinases are used to assess those kinase activities.The arrays described in this paper were already used to determine kinase activities in mammalian systems, but since substrates from LAVENDER B

The dynamic behavior of a stochastic epidemic model CHILD with information intervention and vertical transmission was the concern of this paper.The threshold to judge the extinction and persistence of the disease was obtained.Specifically, when $ Delta < 0 $ ($ Delta $ appears in Section 3), the three classes $ I_t $, $ M_t $, and $ R_t $ appear

In the play Romeo and Juliet, which has become the synonym for the love tragedy, death is represented as the ultimate, all-consuming, and almost nihilistic power that cannot be conquered even by the most pure and passionate love.But, its devastating effect is reduced by the strong, transcendent, and the idealistic vision of love of the two young cr

Nesidioblastosis is a rare condition of organic persistent Games hyperinsulinaemic hypoglycaemia, with fewer than 100 cases since it was first recorded.However, an increasing prevalence suggests previous underdiagnosis due to poor knowledge and awareness.This case describes the presentation, clinical decision-making and unique challenges in diagnos